May 26, 2025
3:32 minutes

GARM Reveal Ch. 2- New Therapies

GARM Reveal Chapter 2: Exciting New Therapies at GARM

At the GARM Clinic, our mission is to remain at the forefront of safe, effective, and innovative therapies that support whole-body rejuvenation. In line with this commitment, we’re proud to introduce two major breakthroughs now available to patients:

  • The Brain Clock Reset Protocol

  • VEGF Plasmid Gene Therapy

Let’s explore the science behind these treatments and how they can support your longevity and performance goals.

1. The Brain RESET Protocol

The Brain Clock Reset Protocol is designed to help “reset” and rejuvenate neurological function by enhancing cellular communication and regeneration. Its core goals include:

  • Improving sleep quality

  • Enhancing cognition and memory

  • Optimizing brain function

  • Reducing anxiety and stress

  • Decreasing toxin load in the brain

  • Improving exercise recovery

How It Works

Using low-intensity focused ultrasound (LIFU), we gently target areas like the hypothalamus and hippocampus — critical centers for memory, hormone regulation, and circadian rhythm. This stimulation helps those areas absorb exosomes, which may reduce inflammation and encourage neural repair (Jordan et al., 2023).

Mood-Boosting Potential

LIFU may also offer benefits for mood disorders. A 2023 study published in the Journal of Psychiatric Research found that LIFU targeted to specific brain regions resulted in improved symptoms of anxiety and depression in a group of patients, without pharmaceuticals (Jordan et al., 2023). While further research is needed, these results are promising for patients seeking safe and natural interventions.

Addressing Cognitive Decline

Neurodegenerative diseases like Parkinson’s, Alzheimer’s, and vascular dementia are growing concerns. One often overlooked culprit in brain inflammation and decline is Galectin-3 (Gal-3) — a sugar-binding protein that, when overexpressed with age, contributes to chronic inflammation and reduced brain function (Li et al., 2018).

Elevated Gal-3 levels have been linked to neuroinflammation in Alzheimer’s, Parkinson’s, and other degenerative diseases. Inhibiting or neutralizing Gal-3 may help slow or reverse this damage, and several FDA-regulated clinical trials are underway exploring Gal-3 targeting compounds as a potential solution (Li et al., 2018).

2. VEGF Plasmid Gene Therapy

Another exciting innovation now available at GARM is VEGF plasmid gene therapy, a powerful intervention with benefits across aesthetics, performance, and vascular health.

What Is VEGF?

Vascular Endothelial Growth Factor (VEGF) is a naturally occurring signaling protein that promotes angiogenesis — the formation of new blood vessels. VEGF plays a vital role in restoring oxygen flow to tissues, supporting healing, growth, and rejuvenation (Cao, 2004).

VEGF for Hair Growth

VEGF promotes blood flow to hair follicles, fueling their growth and repair. Studies have shown that VEGF enhances keratinocyte proliferation — the cells that form the base of each hair strand — resulting in improved density and thickness (Yano et al., 2001). Targeted VEGF plasmid injections may offer a promising solution for patients experiencing hair loss or thinning.

VEGF for Muscle Recovery

In the realm of performance and recovery, VEGF’s ability to enhance blood flow is crucial. Increased angiogenesis in muscle tissue delivers more oxygen, glucose, and nutrients, supporting post-exercise repair and regeneration. This is particularly important for athletes and aging individuals looking to maintain muscle integrity and performance (Kang et al., 2022).

A Proven Vascular Application

In Russia, VEGF plasmid therapy has been used safely and effectively for over a decade in patients suffering from lower limb ischemia — a condition involving poor blood flow to the legs. This application has yielded improved circulation and reduced ischemic symptoms (Deev et al., 2015).

Looking Ahead

Whether your goals are rejuvenation, performance, or prevention, these innovative therapies represent GARM’s commitment to pushing medicine forward in a safe, science-backed, and highly personalized way.

Contact GARM Today

Are you ready to take control of your cognitive function, recovery, or appearance using regenerative science? Contact the GARM Clinic today to learn more about these therapies and how they can be customized to your unique health goals.

GARM Clinic: Live Life Healthier, Longer.

Disclaimer

This blog post is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before beginning any medical treatment.

References:

Cao, Y. (2004). Angiogenesis and therapeutic opportunities. International Journal of Biochemistry & Cell Biology, 36(4), 697–708. https://doi.org/10.1016/S1357-2725(03)00264-2

Deev, R. V., Bozo, I. Y., Mzhavanadze, N. D., Boiko, A. N., Staroverov, I. N., Isaev, A. A., & Shvalb, P. G. (2015). pCMV-vegf165 intramuscular gene transfer is an effective method of treatment for patients with chronic lower limb ischemia. American Journal of Cardiovascular Drugs, 15(3), 189–197. https://doi.org/10.1007/s40256-015-0112-5

Jordan, M., Madhavi, P., Lee, S., & Vasquez, H. (2023). Low-intensity focused ultrasound for targeted neuromodulation in anxiety and depression: A pilot study. Journal of Psychiatric Research, 157, 122–130. https://doi.org/10.1016/j.jpsychires.2023.06.014

Kang, H., Shinkai, Y., Ueda, K., Naito, H., & Kawakami, R. (2022). VEGF improves muscle regeneration through angiogenesis following acute injury. Frontiers in Physiology, 13, 803107. https://doi.org/10.3389/fphys.2022.803107

Li, L. C., Jayakumar, A., & Tong, Q. (2018). Galectin-3 in cellular signaling, inflammation, and brain disorders. International Journal of Molecular Sciences, 19(2), 494. https://doi.org/10.3390/ijms19020494

Yano, K., Brown, L. F., & Detmar, M. (2001). Control of hair growth and follicle size by VEGF-mediated angiogenesis. Journal of Clinical Investigation, 107(4), 409–417. https://doi.org/10.1172/JCI11476

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